Skipping a scene will manually move on from that scene and it will becomes greyed out. As apposed to letting the scene run it's natural course and be completed by the audience.
It is especially useful if a sensor is damaged in a prop and you need to move the show on as if the scene did complete naturally. e.g If one reed switch out of 9 in a jigsaw is damaged then the scene would never move on unless it was skipped.
Skipping the scene can have a different outcome to letting it being completed naturally. This all depends on how your show has been programmed.
All scenes have the option to be skipped. You will find the skip button on the bottom right of each Scene.
The skip function has a safety on it - you need to unlock it then you can skip by clicking on it twice.
This is to prevent a scene skipping accidentally if a rogue click touched the skip button. It has a timeout function, so if you do not press skip after unlocking it will go back to being locked after 4 seconds.